Recombinant Mouse Xpa Protein, Myc/DDK-tagged

• Cat.No.: Xpa-7017M
• Product Overview: Purified recombinant protein of Mouse xeroderma pigmentosum, complementation group A (cDNA clone MGC:36016 IMAGE:4489063), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Involved in DNA excision repair. Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. Required for UV-induced CHEK1 phosphorylation and the recruitment of CEP164 to cyclobutane pyrimidine dimmers (CPD), sites of DNA damage after UV irradiation.
• Molecular Mass: 45.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Xpa xeroderma pigmentosum, complementation group A [ Mus musculus (house mouse) ]
• Official Symbol: Xpa
• Synonyms: Xpa; xeroderma pigmentosum, complementation group A; Xp; Xpac; AI573865; DNA repair protein complementing XP-A cells homolog; xeroderma pigmentosum group A-complementing protein homolog
• Gene ID: 22590
• mRNA Refseq: NM_011728
• Protein Refseq: NP_035858
• UniProt ID: Q64267