Recombinant Mouse Wdr43 Protein, Myc/DDK-tagged

• Cat.No.: Wdr43-6981M
• Product Overview: Purified recombinant protein of Mouse WD repeat domain 43 (Wdr43), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Ribosome biogenesis factor that coordinates hyperactive transcription and ribogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I. Essential for stem cell pluripotency and embryonic development. In the nucleoplasm, recruited by promoter-associated/nascent transcripts and transcription to active promoters where it facilitates releases of elongation factor P-TEFb and paused RNA polymerase II to allow transcription elongation and maintain high-level expression of its targets genes.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 75.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Wdr43 WD repeat domain 43 [ Mus musculus (house mouse) ]
• Official Symbol: Wdr43
• Synonyms: Wdr43; WD repeat domain 43; Wrd43; AU020887; AV024208; mKIAA0007; 2610318G08Rik; WD repeat-containing protein 43
• Gene ID: 72515
• mRNA Refseq: NM_175639
• Protein Refseq: NP_783570
• UniProt ID: Q6ZQL4