Recombinant Mouse Vsig4 Protein, Myc/DDK-tagged

• Cat.No.: Vsig4-6948M
• Product Overview: Purified recombinant protein of Mouse V-set and immunoglobulin domain containing 4 (Vsig4), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Biased expression in liver E18 (RPKM 5.0), liver adult (RPKM 2.5) and 1 other tissue
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 31.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Vsig4 V-set and immunoglobulin domain containing 4 [ Mus musculus (house mouse) ]
• Official Symbol: Vsig4
• Synonyms: VSIG4; V-set and immunoglobulin domain containing 4; V-set and immunoglobulin domain-containing protein 4; complement receptor of the immunoglobulin superfamily; CRIg; Z39IG; BC025105; A530061A11; MGC36211
• Gene ID: 278180
• mRNA Refseq: NM_177789
• Protein Refseq: NP_808457
• UniProt ID: F6TUL9

Reviews

11/08/2021

Stable performance, excellent performance in a variety of experiments.

10/01/2021

No side effects, high safety.

03/13/2021

It has good antigenicity and can induce target immune response.

Q&As

What is the relationship of VSIG4 to other genes or proteins?

VSIG4 has a complex relationship with other genes or proteins, and can interact with other genes or proteins and participate in a variety of biochemical reactions.

How can the disease be treated by regulating the levels of VSIG4?

There are no drugs that directly regulate VSIG4 levels, but they can affect VSIG4 expression and function by modulating the immune system.

How to detect and analyze mutations in VSIG4?

Mutations in VSIG4 can be detected and analyzed by methods such as whole-genome sequencing or target region sequencing to understand the impact of mutations on protein structure and function.

What is the specific role of VSIG4 in tumor immunity?

VSIG4 plays an important role in tumor immunity, which can inhibit the activation and function of T cells and NK cells, thereby promoting tumor growth and metastasis.

How to study the regulatory mechanism of VSIG4?

Studying the regulatory mechanism of VSIG4 requires a combination of various experimental methods and techniques, such as gene knockout, transcriptome analysis, and protein-protein interactions.

What are the mutation types of VSIG4?

The types of mutations in VSIG4 include point mutations, insertions/deletions, duplications, etc., which can cause structural and functional abnormalities of the protein.