Recombinant Mouse Usp21 Protein, Myc/DDK-tagged

• Cat.No.: Usp21-6870M
• Product Overview: Purified recombinant protein of mouse full-length ubiquitin specific peptidase 21 (Usp21), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Deubiquitinates histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A releaves the repression of di- and trimethylation of histone H3 at 'Lys-4', resulting in regulation of transcriptional initiation. Regulates gene expression via histone H2A deubiquitination. Also capable of removing NEDD8 from NEDD8 conjugates but has no effect on Sentrin-1 conjugates. Deubiquitinates BAZ2A/TIP5 leading to its stabilization.
• Molecular Mass: 62.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Usp21 ubiquitin specific peptidase 21 [ Mus musculus (house mouse) ]
• Official Symbol: Usp21
• Synonyms: USP21; ubiquitin specific peptidase 21; ubiquitin carboxyl-terminal hydrolase 21; ubiquitin thioesterase 21; deubiquitinating enzyme 21; ubiquitin thiolesterase 21; ubiquitin specific protease 21; ubiquitin specific protease 23; ubiquitin-specific-processing protease 21; Usp16; Usp23; ESTM28; W53272
• Gene ID: 30941
• mRNA Refseq: NM_013919
• Protein Refseq: NP_038947
• UniProt ID: Q9QZL6