Recombinant Mouse Ttr Protein, Myc/DDK-tagged

• Cat.No.: Ttr-6725M
• Product Overview: Purified recombinant protein of mouse full-length transthyretin (Ttr), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: This gene encodes a carrier protein responsible for the transport of thyroid hormones and retinol. The protein consists of a tetramer of identical subunits. Due to increased stability of the tetramer form of this encoded protein in mouse, compared to the human protein, this gene product has a reduced tendency to form amyloid fibrils. In humans, this protein binds beta-amyloid preventing its aggregation and providing a neuroprotective role in Alzheimer's disease. [provided by RefSeq, Mar 2010]
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 15.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Ttr transthyretin [ Mus musculus (house mouse) ]
• Official Symbol: Ttr
• Synonyms: TTR; transthyretin; D17860; AA408768; AI787086; prealbumin; MGC107649
• Gene ID: 22139
• mRNA Refseq: NM_013697
• Protein Refseq: NP_038725
• UniProt ID: P07309