Recombinant Mouse Trim58 Protein, Myc/DDK-tagged

• Cat.No.: Trim58-6660M
• Product Overview: Purified recombinant protein of mouse full-length tripartite motif-containing 58 (Trim58), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: E3 ubiquitin ligase induced during late erythropoiesis. Directly binds and ubiquitinates the intermediate chain of the microtubule motor dynein (DYNC1LI1/DYNC1LI2), stimulating the degradation of the dynein holoprotein complex. May participate in the erythroblast enucleation process through regulation of nuclear polarization.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 55.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Trim58 tripartite motif-containing 58 [ Mus musculus (house mouse) ]
• Official Symbol: Trim58
• Synonyms: TRIM58; tripartite motif-containing 58; tripartite motif-containing protein 58; Gm16; Gm1783; RP23-128D9.6
• Gene ID: 216781
• mRNA Refseq: NM_001039047
• Protein Refseq: NP_001034136
• UniProt ID: Q5NCC9