Recombinant Mouse triggering receptor expressed on myeloid cells 2 Protein, StrepII tagged

• Cat.No.: Trem2-256M
• Product Overview: Recombinant mouse TREM2 protein (Q99NH8-1) (Leu 19-Ser 171) with a Strep II tag at the C-terminus was expressed HEK293.

Specification

• Species: Mouse
• Source: HEK293
• Tag: Strep II
• Protein Length: 19-171aa
• Description: Triggering receptor expressed on myeloid cells 2 (TREM2) is a protein that in humans is encoded by the TREM2 gene. TREM2 is expressed on macrophages, immature monocyte-derived dendritic cells, osteoclasts, and microglia, which are immune cells in the central nervous system. In the liver, TREM2 is expressed by several cell types, including macrophages, that respond to injury. In the intestine, TREM2 is expressed by myeloid-derived dendritic cells and macrophage. TREM2 is overexpressed in many tumor types and has anti-inflammatory activities. It might therefore be a good therapeutic target.
• Tag: C-StrepII
• Molecular Mass: 18.5 kDa
• Endotoxin: Less than 1.0 EU/μg by the LAL method.
• Purity: >95% as determined by SDS-PAGE.
• Storage: Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade. It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.
• Reconstitution: Reconstitute at 250 μg/mL in sterile water.

Gene Information

• Gene Name: Trem2 triggering receptor expressed on myeloid cells 2 [ Mus musculus (house mouse) ]
• Official Symbol: Trem2
• Synonyms: TREM2; triggering receptor expressed on myeloid cells 2; TREM-2; triggering receptor expressed on monocytes 2; triggering receptor expressed on myeloid cells 2a; triggering receptor expressed on myeloid cells 2b; triggering receptor expressed on myeloid cells 2c; Trem2a; Trem2b; Trem2c
• Gene ID: 83433
• mRNA Refseq: NM_031254
• Protein Refseq: NP_112544
• UniProt ID: Q99NH8