Recombinant Mouse Tnfsf4, FLAG-tagged

• Cat.No.: Tnfsf4-2074M
• Product Overview: Recombinant Mouse Tnfsf4 is produced inHEK 293 Cells. The extracellular domain of mouse CD134L (OX40L) (aa 52-198) is fused at the N-terminus to a linker peptide (8 aa) and a FLAG-tag. MW=28kDa.

Specification

• Species: Mouse
• Source: HEK293
• Tag: Flag
• Protein Length: 52-198 a.a.
• Description: OX40L is the ligand for CD134 and is expressed on such cells as DC2s (a subtype of dendritic cells) enabling amplification of Th2 cell differentiation. OX40L has also been designated CD252 (cluster of differentiation 252).
• Purity: ≥90% (SDS-PAGE).
• Concentration: 0.1mg/ml after reconstitution.
• Formulation: Lyophilized. Contains PBS.
• Endotoxin Content: <0.1EU/µg purified protein (LAL test; Bio Whittaker).
• Reconstitution: Reconstitute with 100µl sterile water.
• Specificity: Binds to human and mouse CD134 (OX40).
• Biological Activity: Activates T cell proliferation.
• Storage: -20°C.

Gene Information

• Gene Name: Tnfsf4 tumor necrosis factor (ligand) superfamily, member 4 [ Mus musculus ]
• Synonyms: Tnfsf4; tumor necrosis factor (ligand) superfamily, member 4; Ath1; gp34; Ath-1; Ox40l; TXGP1; CD134L; OX-40L; Txgp1l; Tnfsf4; tumor necrosis factor ligand superfamily member 4; OX40 ligand; atherosclerosis 1; tax-transcriptionally activated glycoprotein 1 ligand
• Gene ID: 22164
• mRNA Refseq: NM_009452
• Protein Refseq: NP_033478
• UniProt ID: P43488
• Chromosome Location: 1 H2.1; 1 84.9 cM
• Pathway: Cytokine-cytokine receptor interaction
• Function: cytokine activity; tumor necrosis factor receptor binding; tumor necrosis factor receptor superfamily binding