Recombinant Mouse Tnfrsf23, Fc Chimera

• Cat.No.: Tnfrsf23-2111M
• Product Overview: Recombinant Mouse Tnfrsf23 was produced inHEK 293cells. The extracellular domain of mouse DcTRAIL-R1 (aa 1-160) is fused to the Fc portion of human IgG1. MW = ~52kDa (SDS-PAGE).

Specification

• Species: Mouse
• Source: HEK293
• Tag: Fc
• Protein Length: 1-160 a.a.
• Purity: ≥90% (SDS-PAGE).
• Formulation: Lyophilized. Contains PBS.
• Concentration: 1mg/ml after reconstitution.
• Biological Activity: Inhibits mouse soluble TRAIL-induced apoptosis assessed in human Jurkat T-lymphoma cells and human B cells myeloma (BJAB) in a concentration range of 500-1'000ng/ml.
• Endotoxin Content: <0.1EU/µg purified protein (LAL test; Bio Whittaker).
• Reconstitution: Reconstitute with 50µl sterile distilled water. Further dilutions should be made with medium containing 5% fetal calf serum or other carrier protein.
• Specificity: rmDcTRAIL-R1:Fc binds mouse soluble TRAIL in an ELISA assay. Does not bind human soluble TRAIL.
• Application: Cell surface staining of mouse TRAIL by flow cytometry in combination with PAb to human IgG.
• Stability: Stable for at least 6 months after receipt when stored at -20°C.

Gene Information

• Gene Name: Tnfrsf23 tumor necrosis factor receptor superfamily, member 23 [ Mus musculus ]
• Synonyms: Tnfrsf23; tumor necrosis factor receptor superfamily, member 23; mSOB; Tnfrh1; Dctrailr1; MGC123882; MGC123883; Tnfrsf1al1; mDcTrailr1; tumor necrosis factor receptor superfamily member 23; OTTMUSP00000028319; TNF receptor homolog 1; decoy TRAIL receptor 1; TNF receptor family member SOB; tumor necrosis factor receptor p60 homolog 1; tumor necrosis factor receptor superfamily, member 1a-like 1
• Gene ID: 79201
• mRNA Refseq: NM_024290
• Protein Refseq: NP_077252
• UniProt ID: Q9ER63
• Chromosome Location: 7 F5; 7 69.56 cM
• Function: protein binding; receptor activity