Recombinant Mouse Timm8a1 Protein, Myc/DDK-tagged

• Cat.No.: Timm8a1-6434M
• Product Overview: Purified recombinant protein of mouse full-length translocase of inner mitochondrial membrane 8A1 (Timm8a1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins.
• Molecular Mass: 11.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Timm8a1 translocase of inner mitochondrial membrane 8A1 [ Mus musculus (house mouse) ]
• Official Symbol: Timm8a1
• Synonyms: Timm8a1; translocase of inner mitochondrial membrane 8A1; Ddp; Tim; Ddp1; Fci-1; Tim8a; Fci-12; Timm8a; DXHXS1274; DXHXS1274E; mitochondrial import inner membrane translocase subunit Tim8 A; deafness dystonia protein 1 homolog; translocase of inner mitochondrial membrane 8 homolog a; translocase of inner mitochondrial membrane 8 homolog a1
• Gene ID: 30058
• mRNA Refseq: NM_013898
• Protein Refseq: NP_038926
• UniProt ID: Q9WVA2