Recombinant Mouse Tie1 Protein, Fc-tagged

• Cat.No.: Tie1-7355M
• Product Overview: Recombinant Murine soluble TIE-1 (Val23-Glu749) protein fused with the Fc part of human IgG1 was expressed in CHO.

Specification

• Description: Transmembrane tyrosine-protein kinase that may modulate TEK/TIE2 activity and contribute to the regulation of angiogenesis.
• Source: CHO
• Species: Mouse
• Tag: Fc
• Form: Lyophilized
• Molecular Mass: 260 kDa
• AA Sequence: VDLTLLANLRITDPQRFFLTCVSGEAGAGRSSDPPLLLEKDDRIVRTFPPGQPLYLARNGSHQVTLRGFSKPSDLVGVFSCVGGAGARRTRVLYVHNSPGAHLFPDKVTHTVNKGDTAVLSAHVHKEKQTDVIWKNNGSYFNTLDWQEADDGRFQLQLQNVQPPSSGIYSATYLEASPLGSAFFRLIVRGCGAGRWGPGCVKDCPGCLHGGVCHDHDGECVCPPGFTGTRCEQACREGRFGQSCQEQCPGTAGCRGLTFCLPDPYGCSCGSGWRGSQCQEACAPDHFGADCRLQCQCQNGGTCDRFSGCVCPSGWHGVHCEKSDRIPQILSMATEVEFNIGTMPRINCAAAGNPFPVRGSMKLRKPDGTMLLSTKVIVEPDRTTAEFEVPSLTLGDSGFWECRVSTSGGQDSRRFKVNVKVPPVPLTAPRLLAKQSRQLVVSPLVSFSGDGPISSVRLHYRPQDSTIAWSAIVVDPSENVTLMNLKPKTGYNVRVQLSRPGEGGEGGWGPSALMTTDCPEPLLQPWLESWHVEGPDRLRVSWSLPSVPLSGDGFLLRLWDGARGQERRENISFPQARTALLTGLTPGTHYQLDVRLYHCTLLGPASPPAHVHLPPSGPPAPRHLHAQALSDSEIQLMWQHPEAPSGPISKYIVEIQVAGGSGDPQWMDVDRPEETSIIVRGLNASTRYLFRVRASVQGLGDWSNTVEEATLGNGLQSEDPVRESRAAEEGLTRSDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPMLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK
• Purity: > 90 % by SDS-PAGE and visualized by Silver stain
• Stability: Shelf life: one year from despatch.
• Storage: Store lyophilized at 2-8 centigrade for 6 months or at -20 centigrade long term.
  After reconstitution store the antibody undiluted at 2-8 centigrade for one month or (in aliquots) at -20 centigrade long term.
  Avoid repeated freezing and thawing.
• Storage Buffer: PBS without stabilizers
• Reconstitution: Restore in PBS or medium to a concentration not lower than 50 μg/mL. The lyophilised sTIE-1/Fc is soluble in water and most aqueous buffers.

Gene Information

• Gene Name: Tie1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 [ Mus musculus (house mouse) ]
• Official Symbol: Tie1
• Synonyms: Tie1; tyrosine kinase with immunoglobulin-like and EGF-like domains 1; TI; TIE; tie-; tie-1; D430008P04Rik; tyrosine-protein kinase receptor Tie-1; tyrosine kinase receptor 1; EC 2.7.10.1
• Gene ID: 21846
• mRNA Refseq: NM_011587
• Protein Refseq: NP_035717
• UniProt ID: Q06806