Recombinant Mouse Tcf3 Protein, Myc/DDK-tagged

• Cat.No.: Tcf3-6339M
• Product Overview: Purified recombinant protein of mouse full-length transcription factor 3 (Tcf3), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Transcriptional regulator. Involved in the initiation of neuronal differentiation. Heterodimers between TCF3 and tissue-specific basic helix-loop-helix (bHLH) proteins play major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Dimers bind DNA on E-box motifs: 5'-CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer. Binds to IEB1 and IEB2, which are short DNA sequences in the insulin gene transcription control region.
• Molecular Mass: 67.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Tcf3 transcription factor 3 [ Mus musculus (house mouse) ]
• Official Symbol: Tcf3
• Synonyms: TCF3; transcription factor 3; transcription factor E2-alpha; TCF-3; transcription factor A1; transcription factor E2a; immunoglobulin enhancer-binding factor E12/E47; A1; E12; E2A; E47; ME2; ALF2; Pan1; Pan2; VDIR; Tcfe2a; E12/E47; bHLHb21; AA408400; AW209082
• Gene ID: 21423
• mRNA Refseq: NM_011548
• Protein Refseq: NP_035678
• UniProt ID: P15806