Recombinant Mouse Swap70 Protein, Myc/DDK-tagged

• Cat.No.: Swap70-6236M
• Product Overview: Purified recombinant protein of mouse full-length SWA-70 protein (Swap70), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion.
• Molecular Mass: 69.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Swap70 SWA-70 protein [ Mus musculus (house mouse) ]
• Official Symbol: Swap70
• Synonyms: SWAP70; SWA-70 protein; switch-associated protein 70; SWAP-70; SWAP complex protein, 70 kDa; 70kDa; AV235546
• Gene ID: 20947
• mRNA Refseq: NM_009302
• Protein Refseq: NP_033328
• UniProt ID: Q6A028