Recombinant Mouse Sun3 Protein, Myc/DDK-tagged

• Cat.No.: Sun3-6225M
• Product Overview: Purified recombinant protein of mouse full-length Sad1 and UNC84 domain containing 3 (Sun3), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: As a probable component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. May be involved in nuclear remodeling during sperm head formation in spermatogenenis. A probable SUN3:SYNE1 LINC complex may tether spermatid nuclei to posterior cytoskeletal structures such as the manchette.
• Molecular Mass: 29.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Sun3 Sad1 and UNC84 domain containing 3 [ Mus musculus (house mouse) ]
• Official Symbol: Sun3
• Synonyms: SUN3; Sad1 and UNC84 domain containing 3; SUN domain-containing protein 3; Sad1 and UNC84 domain containing 1; sad1/unc-84 domain-containing protein 1; Sad1 and UNC84 domain-containing protein 3; Sunc1; D630047F21Rik; RP23-219P13.2; MGC130135
• Gene ID: 194974
• mRNA Refseq: NM_177576
• Protein Refseq: NP_808244
• UniProt ID: Q5SS91