Recombinant Mouse Stxbp4 Protein, Myc/DDK-tagged

• Cat.No.: Stxbp4-6211M
• Product Overview: Purified recombinant protein of mouse full-length syntaxin binding protein 4 (cDNA clone MGC:41138 IMAGE:1224878), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. Inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. May also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 58.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Stxbp4 syntaxin binding protein 4 [ Mus musculus (house mouse) ]
• Official Symbol: Stxbp4
• Synonyms: Stxbp4; syntaxin binding protein 4; S; Synip; 6030470M02Rik; syntaxin-binding protein 4; STX4-interacting protein; syntaxin 4-interacting protein
• Gene ID: 20913
• mRNA Refseq: NM_011505
• Protein Refseq: NP_035635
• UniProt ID: Q9WV89