Recombinant Mouse Stip1 protein, His-tagged

• Cat.No.: Stip1-127M
• Product Overview: Recombinant Mouse Stip1(1-543aa) fused with His tag was expressed in E. coli.

Specification

• Species: Mouse
• Source: E.coli
• Tag: His
• Protein Length: 1-543 a.a.
• Description: Stip1, also known as stress induced phosphoprotein 1, belongs to the large group of co-chaperones. The main function of Stip1 is to link Hsp70 and Hsp90 together. Stip1 also modulates the chaperone activities of the linked proteins and possibly interacts with other chaperones and proteins. It forms a complex with HSC70 and HSPCA/HSP-86 and HSPCB/HSP-84, as well as interacting with PACRG.
• Form: Liquid. In 20mM Tris-HCl(pH8.0) containing 0.1M NaCl, 1mM DTT, 10% glycerol
• Molecular Mass: 64.7 kDa (563aa) confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MEQVNELKEK GNKALSAGNI DDALQCYSEA IKLDPQNHVL YSNRSAAYAK KGDYQKAYED GCKTVDLKPD
  WGKGYSRKAA ALEFLNRFEE AKRTYEEGLK HEANNLQLKE GLQNMEARLA ERKFMNPFNL PNLYQKLEND PRTRSLLSDP TYRELIEQLQ
  NKPSDLGTKL QDPRVMTTLS VLLGVDLGSM DEEEEAATPP PPPPPKKEPK PEPMEEDLPE NKKQALKEKE LGNDAYKKKD FDKALKHYDR
  AKELDPTNMT YITNQAAVHF EKGDYNKCRE LCEKAIEVGR ENREDYRQIA KAYARIGNSY FKEEKYKDAI HFYNKSLAEH RTPDVLKKCQ
  QAEKILKEQE RLAYINPDLA LEEKNKGNEC FQKGDYPQAM KHYTEAIKRN PRDAKLYSNR AACYTKLLEF QLALKDCEEC IQLEPTFIKG
  YTRKAAALEA MKDYTKAMDV YQKALDLDSS CKEAADGYQR CMMAQYNRHD SPEDVKRRAM ADPEVQQIMS DPAMRLILEQ MQKDPQALSE
  HLKNPVIAQK IQKLMDVGLI AIR
• Purity: > 95% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml (determined by Absorbance at 280nm)

Gene Information

• Gene Name: Stip1 stress-induced phosphoprotein 1 [ Mus musculus ]
• Official Symbol: Stip1
• Synonyms: STIP1; stress-induced phosphoprotein 1; stress-induced-phosphoprotein 1; mSTI1; IEF SSP 3521; stress-inducible protein; Hsp70/Hsp90 organizing protein; hsc70/Hsp90-organizing protein; Hop; p60; Sti1
• Gene ID: 20867
• mRNA Refseq: NM_016737
• Protein Refseq: NP_058017
• UniProt ID: Q60864
• Chromosome Location: 19; 19 A
• Pathway: Prion diseases, organism-specific biosystem; Prion diseases, conserved biosystem
• Function: Hsp70 protein binding; binding; chaperone binding; protein C-terminus binding