Recombinant Mouse Stab2 Protein, Myc/DDK-tagged

• Cat.No.: Stab2-6154M
• Product Overview: Purified recombinant protein of mouse full-length stabilin 2 (Stab2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Hyaluronan receptor that binds to and mediates endocytosis of hyaluronic acid (HA). Acts also, in different species, as a primary systemic scavenger receptor for heparin (Hep), chondroitin sulfate (CS), dermatan sulfate (DS), nonglycosaminoglycan (GAG), acetylated low-density lipoprotein (AcLDL), pro-collagen propeptides and advanced glycation end products (AGE). May serve to maintain tissue integrity by supporting extracellular matrix turnover or it may contribute to maintaining fluidity of bodily liquids by resorption of hyaluronan. Counter receptor which plays an important role in lymphocyte recruitment in the hepatic vasculature. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. The proteolytically processed short form also functions as an endocytosis receptor for heparin internalisation as well as HA and CS.
• Molecular Mass: 278 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Stab2 stabilin 2 [ Mus musculus (house mouse) ]
• Official Symbol: Stab2
• Synonyms: Stab2; stabilin 2; FELL; STAB; FEEL-; FEEL-2; STAB-2; MFEEL-2; stabilin-2; fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 2; scavenger receptor FEEL-2
• Gene ID: 192188
• mRNA Refseq: NM_138673
• Protein Refseq: NP_619614
• UniProt ID: Q8R4U0