Recombinant Mouse Sox10 Protein, Myc/DDK-tagged

• Cat.No.: Sox10-6049M
• Product Overview: Purified recombinant protein of mouse full-length SRY-box containing gene 10 (cDNA clone MGC:18351 IMAGE:3675437), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Transcription factor that plays a central role in developing and mature glia). Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination. Once induced, MYRF cooperates with SOX10 to implement the myelination program. Transcriptional activator of MITF, acting synergistically with PAX3. Transcriptional activator of MBP, via binding to the gene promoter.
• Molecular Mass: 49.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Sox10 SRY (sex determining region Y)-box 10 [ Mus musculus (house mouse) ]
• Official Symbol: Sox10
• Synonyms: Sox10; SRY (sex determining region Y)-box 10; gt; Dom; Sox; Sox21; transcription factor SOX-10; SRY-box containing gene 10; dominant megacolon; transcription factor SOX-M
• Gene ID: 20665
• mRNA Refseq: NM_011437
• Protein Refseq: NP_035567
• UniProt ID: Q04888