Recombinant Mouse Smad1 Protein, Myc/DDK-tagged

• Cat.No.: Smad1-5949M
• Product Overview: Purified recombinant protein of mouse full-length SMAD family member 1 (Smad1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). May play a role in the initiation and maintenance of spermatogenesis. SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.
• Molecular Mass: 52.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Smad1 SMAD family member 1 [ Mus musculus (house mouse) ]
• Official Symbol: Smad1
• Synonyms: SMAD1; MAD homolog 1 (Drosophila); mothers against decapentaplegic homolog 1; dwf-A; mMad1; Smad 1; dwarfin-A; SMAD family member 1; mad-related protein 1; mothers against DPP homolog 1; mothers-against-DPP-related 1; Mlp1; Madh1; Madr1; MusMLP; AI528653
• Gene ID: 17125
• mRNA Refseq: NM_008539
• Protein Refseq: NP_032565
• UniProt ID: P70340