Recombinant Mouse Slurp1 Protein, Myc/DDK-tagged

• Cat.No.: Slurp1-5947M
• Product Overview: Purified recombinant protein of mouse full-length secreted Ly6/Plaur domain containing 1 (Slurp1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Has an antitumor activity. Was found to be a marker of late differentiation of the skin. Implicated in maintaining the physiological and structural integrity of the keratinocyte layers of the skin. In vitro down-regulates keratinocyte proliferation; the function may involve the proposed role as modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-7-dependent nAChR currents in an allosteric manner. In T cells may be involved in regulation of intracellular Ca2+ signaling. Seems to have a immunomodulatory function in the cornea. The function may implicate a possible role as a scavenger receptor for PLAU thereby blocking PLAU-dependent functions of PLAUR such as in cell migration and proliferation.
• Molecular Mass: 12 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Slurp1 secreted Ly6/Plaur domain containing 1 [ Mus musculus (house mouse) ]
• Official Symbol: Slurp1
• Synonyms: SLURP1; secreted Ly6/Plaur domain containing 1; secreted Ly-6/uPAR-related protein 1; Ars component B; secreted Ly-6/uPAR related protein 1; ARS; ArsB; Slurp-1; AI415082; 1110021N19Rik; MGC130552
• Gene ID: 57277
• mRNA Refseq: NM_020519
• Protein Refseq: NP_065265
• UniProt ID: Q9Z0K7