Recombinant Mouse Slc9a3r1 Protein, Myc/DDK-tagged

• Cat.No.: Slc9a3r1-5941M
• Product Overview: Purified recombinant protein of mouse full-length solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 (Slc9a3r1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for recycling of internalized ADRB2. Was first known to play a role in the regulation of the activity and subcellular location of SLC9A3. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May enhance Wnt signaling. May participate in HTR4 targeting to microvilli. Involved in the regulation of phosphate reabsorption in the renal proximal tubules. Involved in sperm capacitation. May participate in the regulation of the chloride and bicarbonate homeostasis in spermatozoa.
• Molecular Mass: 38.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Slc9a3r1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 [ Mus musculus (house mouse) ]
• Official Symbol: Slc9a3r1
• Synonyms: SLC9A3R1; solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1; Na(+)/H(+) exchange regulatory cofactor NHE-RF1; EBP50; regulatory cofactor of Na(+)/H(+) exchanger; sodium-hydrogen exchanger regulatory factor 1; ezrin-radixin-moesin-binding phosphoprotein 50; solute carrier family 9 isoform A3 regulatory factor 1; solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulator 1; EBP-50; NHE-RF; NHERF1; NHERF-1; MGC95776
• Gene ID: 26941
• mRNA Refseq: NM_012030
• Protein Refseq: NP_036160
• UniProt ID: P70441