Recombinant Mouse Slc6a4 Protein, His-tagged

• Cat.No.: Slc6a4-2079M
• Product Overview: Recombinant Mouse Slc6a4 Protein (Ser483-Val630) with N-His tag was expressed in E. coli.

Specification

• Description: Enables monoamine transmembrane transporter activity; neurotransmitter transmembrane transporter activity; and nitric-oxide synthase binding activity. Involved in several processes, including brain morphogenesis; serotonin uptake; and social behavior. Acts upstream of or within cellular response to organic substance. Located in focal adhesion and synapse. Is expressed in several structures, including early conceptus; liver; nervous system; ovary; and polar body. Used to study autism spectrum disorder and sudden infant death syndrome. Human ortholog(s) of this gene implicated in several diseases, including alcohol use disorder; alexithymia; anxiety disorder (multiple); heart disease (multiple); and mental depression (multiple). Orthologous to human SLC6A4 (solute carrier family 6 member 4).
• Source: E. coli
• Species: Mouse
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 16.6 kDa
  Accurate Molecular Mass: 20 kDa
• Protein length: Ser483-Val630
• Purity: > 97%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: Slc6a4 solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 [ Mus musculus (house mouse) ]
• Official Symbol: Slc6a4
• Synonyms: Slc6a4; solute carrier family 6 (neurotransmitter transporter, serotonin), member 4; Htt; Sert; 5-HTT; AI323329; sodium-dependent serotonin transporter; 5-hydroxytryptamine (serotonin) transporter; 5HT transporter; 5HTT; Sodium-dependent serotonin transporter (5HT transporter) (5HTT); solute carrier family 6 member 4
• Gene ID: 15567
• mRNA Refseq: NM_010484
• Protein Refseq: NP_034614
• UniProt ID: Q60857