Recombinant Mouse Slc27a2 Protein, Myc/DDK-tagged

• Cat.No.: Slc27a2-5917M
• Product Overview: Purified recombinant protein of mouse full-length solute carrier family 27 (fatty acid transporter), member 2 (Slc27a2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Acyl CoA synthetase that activates long-chain and very long-chain fatty acids (VLCFAs) by catalyzing the formation of fatty acyl-CoA. Can also activate branched-chain fatty acids such as phytanic acid and pristanic acid. Does not activate C24 bile acids, cholate and chenodeoxycholate. In vitro, activates 3-alpha,7-alpha,12-alpha-trihydroxy- 5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. Exhibits long-chain fatty acids (LCFA) transport activity and plays an important role in hepatic fatty acid uptake.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 70.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Slc27a2 solute carrier family 27 (fatty acid transporter), member 2 [ Mus musculus (house mouse) ]
• Official Symbol: Slc27a2
• Synonyms: SLC27A2; solute carrier family 27 (fatty acid transporter), member 2; very long-chain acyl-CoA synthetase; FATP-2; THCA-CoA ligase; fatty acid transport protein 2; long-chain-fatty-acid--CoA ligase; solute carrier family 27 member 2; very long-chain-fatty-acid-CoA ligase; fatty-acid-coenzyme A ligase, very long-chain 1; very long-chain acyl-Coenzyme A dehydrogenase synthase; VLCS; Vlac; FATP2; Vlacs; ACSVL1
• Gene ID: 26458
• mRNA Refseq: NM_011978
• Protein Refseq: NP_036108
• UniProt ID: O35488