Recombinant Mouse Slc22a5 Protein, His&GST-tagged

• Cat.No.: Slc22a5-2063M
• Product Overview: Recombinant Mouse Slc22a5 Protein (Met1-Pro278) with N-His&GST tag was expressed in E. coli.

Specification

• Description: Enables (R)-carnitine transmembrane transporter activity. Involved in (R)-carnitine transmembrane transport and transport across blood-brain barrier. Acts upstream of or within several processes, including adult heart development; carnitine metabolic process; and carnitine transport. Located in brush border membrane. Is expressed in several structures, including liver; metanephros; nasal cavity mucosa; spleen; and testis. Used to study systemic primary carnitine deficiency disease. Human ortholog(s) of this gene implicated in Crohn's disease; cardiomyopathy; inherited metabolic disorder; and systemic primary carnitine deficiency disease. Orthologous to human SLC22A5 (solute carrier family 22 member 5).
• Source: E. coli
• Species: Mouse
• Tag: His&GST
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 61.6 kDa
  Accurate Molecular Mass: 62 kDa
• Protein length: Met1-Pro278
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: Slc22a5 solute carrier family 22 (organic cation transporter), member 5 [ Mus musculus (house mouse) ]
• Official Symbol: Slc22a5
• Synonyms: Slc22a5; solute carrier family 22 (organic cation transporter), member 5; jvs; Lstpl; Octn2; solute carrier family 22 member 5; high-affinity sodium-dependent carnitine cotransporter; juvenile visceral steatosis; organic cation/carnitine transporter 2
• Gene ID: 20520
• mRNA Refseq: NM_011396
• Protein Refseq: NP_035526
• UniProt ID: Q9Z0E8