Recombinant Mouse Slc16a1 Protein, Myc/DDK-tagged

• Cat.No.: Slc16a1-5905M
• Product Overview: Purified recombinant protein of mouse full-length solute carrier family 16 (monocarboxylic acid transporters), member 1 (Slc16a1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to a high-fat diet by modulating the cellular levels of lactate and pyruvate, small molecules that contribute to the regulation of central metabolic pathways and insulin secretion, with concomitant effects on plasma insulin levels and blood glucose homeostasis.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 53.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Slc16a1 solute carrier family 16 (monocarboxylic acid transporters), member 1 [ Mus musculus (house mouse) ]
• Official Symbol: Slc16a1
• Synonyms: SLC16A1; solute carrier family 16 (monocarboxylic acid transporters), member 1; monocarboxylate transporter 1; MCT 1; solute carrier family 16 member 1; Mct1; AL022710
• Gene ID: 20501
• mRNA Refseq: NM_009196
• Protein Refseq: NP_033222
• UniProt ID: P53986