Recombinant Mouse Slc14a1 Protein, MYC/DDK-tagged

• Cat.No.: Slc14a1-029M
• Product Overview: Purified recombinant protein of full-length mouse solute carrier family 14 (urea transporter), member 1 (Slc14a1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Urea channel that facilitates transmembrane urea transport down a concentration gradient. A constriction of the transmembrane channel functions as selectivity filter through which urea is expected to pass in dehydrated form. The rate of urea conduction is increased by hypotonic stress. Plays an important role in the kidney medulla collecting ducts, where it allows rapid equilibration between the lumen of the collecting ducts and the interstitium, and thereby prevents water loss driven by the high concentration of urea in the urine. Facilitates urea transport across erythrocyte membranes. May also play a role in transmembrane water transport, possibly by indirect means.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 42.6 kDa
• Purity: >80%, as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 ug/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Slc14a1 solute carrier family 14 (urea transporter), member 1 [ Mus musculus (house mouse) ]
• Official Symbol: Slc14a1
• Synonyms: Slc14a1; solute carrier family 14 (urea transporter), member 1; UT-B; Utb1; 2610507K20Rik; 3021401A05Rik; urea transporter 1; solute carrier family 14 member 1; urea transporter B; urea transporter, erythrocyte
• Gene ID: 108052
• mRNA Refseq: NM_028122
• Protein Refseq: NP_082398
• UniProt ID: Q8VHL0