Recombinant Mouse SIRT1 Protein, His-tagged

• Cat.No.: SIRT1-100M
• Product Overview: Recombinant Mouse sirtuin 1 (aa 2-737) was expressed in E. coli and fused with the N-terminal His-tag.

Specification

• Species: Mouse
• Source: E.coli
• Tag: His
• Protein Length: 2-737 a.a.
• Description: The SIRT family of genes are highly conserved from prokaryotes to eukaryotes and are involved in diverse processes including transcriptional regulation, cell cycle progression, DNA damage repair and aging. Sirtuins utilize NAD+ as a substrate to catalyze deacetylation of specific acetylated protein and histones. SIRT1 has been shown to be induced by caloric restriction (CR) in several tissues and SIRT1 mediated deacetylase activity attenuates B-amyloid content in the brain during CR.
• Form: 55 mM Tris-HCl, pH 8.2, 150 mM NaCl
• Molecular Mass: ~100kDa (SDS-PAGE)
• Storage: Store at +4 centigrade for immediate use, or aliquot and store at -20 centigrade for up to 3 months. Avoid repeat freeze-thaw cycles.

Gene Information

• Gene Name: Sirt1 sirtuin 1 [ Mus musculus (house mouse) ]
• Official Symbol: Sirt1
• Synonyms: SIRT1 Protein, SIR2-like protein 1 Protein, SIR2alpha Protein, SIR2L1 Protein, Sirtuin 1 Protein, Sir2-like 1 Protein, Sirtuin type 1 Protein, HSIR2 Protein, HSIRT1 Protein
• Gene ID: 93759
• mRNA Refseq: NM_019812.3
• Protein Refseq: NP_062786.1
• UniProt ID: Q923E4