Recombinant Mouse Sh2b3 protein, His & T7-tagged
Cat.No. : | Sh2b3-1557M |
Product Overview : | Recombinant Mouse Sh2b3 aa. (Ala225~Val447 (Accession # O09039)) fused with N-terminal His & T7 tag was produced in E. coli cells. |
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Description : | This gene encodes a member of the SH2B family of adapter proteins that play an important role in T cell receptor signaling. This gene is preferentially expressed in hematopoietic stem cells, hematopoietic progenitors, pre and immature B cells, as well as megakaryocytes and mastocytes. In hematopoietic stem cells, the encoded protein is a key regulator of self-renewal, proliferation and apoptosis. Mice lacking the encoded protein exhibit pre and immature B cell expansion in spleen and the bone marrow. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 28.3kDa |
Protein length : | Ala225~Val447 |
Endotoxin : | <1.0EU per 1ug (determined by the LAL method) |
Purity : | >95% |
Applications : | SDS-PAGE; WB; ELISA; IP. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Storage buffer : | Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl. |
Reconstitution : | Reconstitute in sterile PBS, pH7.2-pH7.4. |
Isoelectric Point : | 6.3 |
Gene Name | Sh2b3 SH2B adaptor protein 3 [ Mus musculus (house mouse) ] |
Official Symbol | Sh2b3 |
Synonyms | Sh2b3; SH2B adaptor protein 3; Lnk; AI429800; linker of T-cell receptor pathways; lymphocyte-specific adapter protein Lnk; signal transduction protein Lnk |
Gene ID | 16923 |
mRNA Refseq | NM_001306126.1 |
Protein Refseq | NP_001293055.1 |
UniProt ID | O09039 |
Not For Human Consumption!
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