Recombinant Mouse Scn3b Protein, Myc/DDK-tagged

• Cat.No.: Scn3b-5716M
• Product Overview: Purified recombinant protein of mouse full-length sodium channel, voltage-gated, type III, beta (Scn3b), transcript variant 1, with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: Myc&DDK
• Description: Modulates channel gating kinetics. Causes unique persistent sodium currents. Inactivates the sodium channel opening more slowly than the subunit beta-1. Its association with NFASC may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons.
• Molecular Mass: 24.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Scn3b sodium channel, voltage-gated, type III, beta [ Mus musculus (house mouse) ]
• Official Symbol: Scn3b
• Synonyms: Scn3b; sodium channel, voltage-gated, type III, beta; Scnb3; 1110001K16Rik; 4833414B02Rik; sodium channel subunit beta-3; brain and heart sodium channel beta 3 subunit
• Gene ID: 235281
• mRNA Refseq: NM_153522
• UniProt ID: Q8BHK2