Recombinant Mouse Sacm1l Protein, Myc/DDK-tagged

• Cat.No.: Sacm1l-5677M
• Product Overview: Purified recombinant protein of mouse full-length SAC1 suppressor of actin mutations 1-like (yeast) (Sacm1l), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes an integral membrane protein, which is localized to the endoplasmic reticulum, and functions as a phosphoinositide phosphatase that hydrolyzes phosphatidylinositol 3-phosphate, phosphatidylinositol 4-phosphate, and phosphatidylinositol 3,5-bisphosphate. Deletion of this gene in mouse results in preimplantation lethality. Other studies suggest that this gene is also involved in the organization of golgi membranes and mitotic spindles. Two isoforms are predicted to be produced from the same mRNA by the use of alternative in-frame translation termination codons via a stop codon readthrough mechanism.
• Molecular Mass: 67.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Sacm1l SAC1 suppressor of actin mutations 1-like (yeast) [ Mus musculus (house mouse) ]
• Official Symbol: Sacm1l
• Synonyms: SACM1L; SAC1 (suppressor of actin mutations 1, homolog)-like (S. cerevisiae); phosphatidylinositide phosphatase SAC1; polyphosphatidylinositol phosphatase; suppressor of actin mutations 1-like protein; SAC1; Sac1p; mKIAA0851
• Gene ID: 83493
• mRNA Refseq: NM_030692
• Protein Refseq: NP_109617
• UniProt ID: Q9EP69