Recombinant Mouse S100a6, His-tagged

• Cat.No.: S100a6-3552M
• Product Overview: Recombinant mouse S100a6protein, fused to His-tag at N-terminus, was expressed in E. coli andpurified by using conventional chromatography techniques.

Specification

• Cat. No.: S100a6-3552M
• Description: S100calcium binding protein A6 (S100a6) belongsto the S100 family. S100 family is containing 2 EF-hand calcium-binding motifs.S100 proteins regulate a number of cellular processes such as cell cycle progressionsand differentiation. S100a6 plays a role inthe reorganization of the actin cytoskeleton and in cell mobility. This is a specifictarget of S-100B protein in vivo. The binding of S100a6 to S100B is stabilized by S100B-bound calcium and zinc.It associates with both Annexin XI and CacyBP (Calcyclin-binding protein). Itfunctions to activate several processes along the calcium signal transductionpathway including the regulation of cell growth, proliferation, secretion andexocytosis.
• Form: Liquid. In 20mMTris-HCl buffer (pH 8.0) containing 1mM DTT ,30% glycerol, 100mM NaCl.
• Molecular Weight: 12.2 kDa(109 aa), confirmed by MALDI-TOF.
• Purity: > 95%by SDS - PAGE
• Concentration: 0.5 mg/ml(determined by Bradford assay)
• Sequences of aminoacids: MGSSHHHHHHSSGLVPRGSH MACPLDQAIG LLVAIFHKYS GKEGDKHTLS KKELKELIQKELTIGSKLQD AEIARLMDDL DRNKDQEVNF QEYVAFLGAL ALIYNEALK
• Storage: Can bestored at +4°C short term (1-2 weeks). For long term storage, aliquot andstore at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: S100a6 S100 calcium bindingprotein A6 (calcyclin) [ Mus musculus ]
• Official Symbol: S100a6
• Synonyms: S100a6; S100 calcium binding protein A6(calcyclin); 2A9; PRA; 5B10; Cacy; CALCYCLIN; protein S100-A6; S100calcium-binding protein A6; prolactin receptor-associated protein; calciumbinding protein A6 (calcyclin)
• Gene ID: 20200
• mRNA Refseq: NM_011313
• Protein Refseq: NP_035443
• UniProt ID: P14069
• Chromosome Location: 3 F1-F2; 3 43.6 cM
• Pathway: Prostaglandin Synthesis and Regulation
• Function: S100 beta binding; calcium ion binding;calcium-dependent protein binding; ion transmembrane transporter activity;metal ion binding; protein binding; protein homodimerization activity;tropomyosin binding; zinc ion binding