Recombinant Mouse S100 Calcium Binding Protein A6 (Calcyclin)

• Cat.No.: S100a6-4566M
• Product Overview: S100A6 also called Calcyclin has been purified by HPLC (see Kuznicki et al. (1989) Biochem. J. 263: 951-956).

Specification

• Cat. No.: S100a6-4566M
• Description: S100A6 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized either in the cytoplasm or the nucleus of a wide range of cells. S100 proteins are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. There are at least 13 members in the S100 gene family, which are located as a cluster on chromosome 1q21. S100A6 may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of the S100A6 gene are implicated in melanoma.
• Source: Mouse
• Form: The protein was lyophilized from a concentrated solution (1mg/ml) containing no additives.
• Purity: Greater than 90% as determined by SDS-PAGE.
• Physical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.
• Solubility: It is recommended to reconstitute the lyophilized Mouse S100A6 in sterile 18Mμ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
• Storage: Lyophilized Mouse S100A6 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Mouse S100A6 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
• Tag: Non

Gene Information

• Gene Name: S100a6 S100 calcium binding protein A6 (calcyclin) [ Mus musculus ]
• Official Symbol: S100a6
• Synonyms: S100a6; S100 calcium binding protein A6 (calcyclin); 2A9; PRA; 5B10; Cacy; CALCYCLIN; protein S100-A6; S100 calcium-binding protein A6prolactin receptor; -associated protein; calcium binding protein A6 (calcyclin)
• Gene ID: 20200
• mRNA Refseq: NM_011313
• Protein Refseq: NP_035443
• UniProt ID: P14069
• Chromosome Location: 43.6 cM
• Pathway: Prostaglandin Synthesis and Regulation
• Function: S100 beta binding; calcium ion binding; protein binding; calcium-dependent protein binding; ion transmembrane transporter activity; metal ion binding; protein homodimerization activity; tropomyosin binding