Recombinant Mouse Rora Protein, Myc/DDK-tagged

• Cat.No.: Rora-5574M
• Product Overview: Purified recombinant protein of mouse full-length RAR-related orphan receptor alpha (cDNA clone MGC:5892 IMAGE:3592667), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm. Three transcript variants encoding different isoforms have been found for this gene.
• Molecular Mass: 87.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Rora RAR-related orphan receptor alpha [ Mus musculus (house mouse) ]
• Official Symbol: Rora
• Synonyms: Rora; RAR-related orphan receptor alpha; sg; Nr1; ROR1; ROR2; ROR3; Nr1f1; nmf267; tmgc26; staggerer; 9530021D13Rik; nuclear receptor ROR-alpha; RAR-related orphan receptor A; nuclear receptor RZR-alpha; nuclear receptor subfamily 1 group F member 1; retinoid-related orphan receptor-alpha
• Gene ID: 19883
• mRNA Refseq: NM_013646
• Protein Refseq: NP_038674
• UniProt ID: P51448