Recombinant Mouse Rnf166 Protein, Myc/DDK-tagged

• Cat.No.: Rnf166-5550M
• Product Overview: Purified recombinant protein of mouse full-length ring finger protein 166 (Rnf166), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: E3 ubiquitin-protein ligase that promotes the ubiquitination of different substrates. In turn, participates in different biological processes including interferon production or autophagy. Plays a role in the activation of RNA virus-induced interferon-beta production by promoting the ubiquitination of TRAF3 and TRAF6. Plays also a role in the early recruitment of autophagy adapters to bacteria. Mediates 'Lys-29' and 'Lys-33'-linked ubiquitination of SQSTM1 leading to xenophagic targeting of bacteria and inhibition of their replication.
• Molecular Mass: 26.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Rnf166 ring finger protein 166 [ Mus musculus (house mouse) ]
• Official Symbol: Rnf166
• Synonyms: RNF166; ring finger protein 166; RING finger protein 166; zinc finger protein 313; zinc finger protein 228; Zfp313l; AW555115; 1110031E24Rik
• Gene ID: 68718
• mRNA Refseq: NM_001033142
• Protein Refseq: NP_001028314
• UniProt ID: Q3U9F6