Recombinant Mouse Ribosomal Protein S6 Kinase, Polypeptide 4, GST-tagged

• Cat.No.: Rps6ka4-1062M
• Product Overview: Recombinant full-length mouse Rps6ka4 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Cat. No.: Rps6ka4-1062M
• Description: Rps6ka4 or mitogen- and stress-activated protein kinase-2 is a member of the serine/threonine kinases family that contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including CREB1 and c-fos. Rps6ka4 is also known as ribosomal protein S6 kinase 4 (RPS6KA4) that are activated by the mitogen-activated protein kinases ERK1, ERK2, and p38.
• Applications: Kinase Assay; Western Blot
• Molecular Weight: 114 kDa
• Expression System: Sf9 insect cells using baculovirus
• Species: Mouse
• Form: Recombinant protein stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
• Purity: > 95%
• Specific Activity: 9 nmol/min/mg
• Concentration: 0.1 ug/ul
• Sequences: full-length
• Storage: Store product at -70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Gene Information

• Gene Name: Rps6ka4 ribosomal protein S6 kinase, polypeptide 4 [ Mus musculus ]
• Official Symbol: Rps6ka4
• Synonyms: Rps6ka4; ribosomal protein S6 kinase, polypeptide 4; Msk2; 90kDa; mMSK2; AI848992; 1110069D02Rik; ribosomal protein S6 kinase alpha-4; RLSK; S6K-alpha-4; RSK-like protein kinase; 90 kDa ribosomal protein S6 kinase 4; mitogen- and stress-activated protein kinase-2; ribosomal protein S6 kinase, 90kD, polypeptide 4; nuclear mitogen- and stress-activated protein kinase 2; EC 2.7.11
• Gene ID: 56613
• mRNA Refseq: NM_019924
• Protein Refseq: NP_064308
• UniProt ID: Q9Z2B9
• Chromosome Location: 19A
• Pathway: Axon guidance; Insulin Signaling; L1CAM interactions; MAPK signaling pathway; Neurotrophin signaling pathway; Recycling pathway of L1;Signal transduction by L1
• Function: nucleotide binding; protein binding; protein kinase activity; protein serine/threonine kinase activity; transferase activity; transferase activity, transferring phosphorus-containing groups