Recombinant Mouse REN1 Protein

• Cat.No.: REN1-809M
• Product Overview: Recombinant Mouse REN1 protein without tag was expressed in HEK293.

Specification

• Species: Mouse
• Source: HEK293
• Protein Length: 402
• Description: Enables endopeptidase activity. Acts upstream of or within with a positive effect on regulation of blood pressure. Acts upstream of or within several processes, including drinking behavior; male gonad development; and regulation of systemic arterial blood pressure by renin-angiotensin. Located in extracellular space. Is expressed in several structures, including alimentary system; brain; extraembryonic component; genitourinary system; and trunk. Human ortholog(s) of this gene implicated in essential hypertension; familial juvenile hyperuricemic nephropathy; hand, foot and mouth disease; hypertension; and portal hypertension. Orthologous to human REN (renin).
• Form: Lyophilized
• Molecular Mass: 43.2 kDa
• AA Sequence: MDRRRMPLWALLLLWSPCTFSLPTRTATFERIPLKKMPSVREILEERGVDMTRLSAEWGVFTKRPSLTNLTSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPLIPFMLAKFDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLGGSDPQHYQGNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSLKLIMQALGAKEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTLALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR
• Purity: > 98%
• Applications: WB; ELISA; FACS; FC
• Stability: This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use.
• Storage: At -20 centigrade.
• Concentration: 1 mg/mL
• Storage Buffer: PBS (pH 7.4-7.5). Sterile-filtered colorless solution.
• Reconstitution: Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.

Gene Information

• Gene Name: Ren1 renin 1 structural [ Mus musculus (house mouse) ]
• Official Symbol: REN1
• Synonyms: REN1; renin 1 structural; renin-1; renin b; kidney renin; aspartyl-protease; angiotensinogenase; Ren; Rnr; Rn-1; Ren-1; Ren-A; Ren1c; Ren1d; D19352
• Gene ID: 19701
• mRNA Refseq: NM_031192
• Protein Refseq: NP_112469
• UniProt ID: P06281