Recombinant Mouse Rassf7 Protein, Myc/DDK-tagged

• Cat.No.: Rassf7-5398M
• Product Overview: Purified recombinant protein of mouse full-length Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 (Rassf7), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Following prolonged stress, anti-apoptotic effect stops because of degradation of RASSF7 protein via the ubiquitin-proteasome pathway. Required for the activation of AURKB and chromosomal congression during mitosis where it stimulates microtubule polymerization.
• Molecular Mass: 39.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Rassf7 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 [ Mus musculus (house mouse) ]
• Official Symbol: Rassf7
• Synonyms: RASSF7; Ras association (RalGDS/AF-6) domain family (N-terminal) member 7; ras association domain-containing protein 7; Ras association (RalGDS/AF-6) domain family 7; AW210608; 2400009B11Rik
• Gene ID: 66985
• mRNA Refseq: NM_025886
• Protein Refseq: NP_080162
• UniProt ID: Q9DD19