Recombinant Mouse Rangap1 Protein, Myc/DDK-tagged

• Cat.No.: Rangap1-5370M
• Product Overview: Purified recombinant protein of mouse full-length RAN GTPase activating protein 1 (Rangap1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: GTPase activator for RAN. Converts cytoplasmic GTP-bound RAN to GDP-bound RAN, which is essential for RAN-mediated nuclear import and export. Mediates dissociation of cargo from nuclear export complexes containing XPO1, RAN and RANBP2 after nuclear export. Required for postimplantation embryonic development.
• Molecular Mass: 63.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Rangap1 RAN GTPase activating protein 1 [ Mus musculus (house mouse) ]
• Official Symbol: Rangap1
• Synonyms: RANGAP1; RAN GTPase activating protein 1; ran GTPase-activating protein 1; Fug1; C79654; mKIAA1835
• Gene ID: 19387
• mRNA Refseq: NM_011241
• Protein Refseq: NP_035371
• UniProt ID: P46061