Recombinant Mouse Rab27b Protein, Myc/DDK-tagged

• Cat.No.: Rab27b-5303M
• Product Overview: Purified recombinant protein of mouse full-length RAB27B, member RAS oncogene family (Rab27b), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion. Plays a role in NTRK2/TRKB axonal anterograde transport by facilitating the association of NTRK2/TRKB with KLC1. May be involved in targeting uroplakins to urothelial apical membranes.
• Molecular Mass: 24.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Rab27b RAB27B, member RAS oncogene family [ Mus musculus (house mouse) ]
• Official Symbol: Rab27b
• Synonyms: RAB27B; RAB27b, member RAS oncogene family; ras-related protein Rab-27B; 2310021G14Rik; B130064M09Rik
• Gene ID: 80718
• mRNA Refseq: NM_030554
• Protein Refseq: NP_085031
• UniProt ID: Q99P58