Recombinant Mouse Rab12 Protein, Myc/DDK-tagged

• Cat.No.: Rab12-5289M
• Product Overview: Purified recombinant protein of mouse full-length RAB12, member RAS oncogene family (Rab12), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor. Involved in autophagy.
• Molecular Mass: 27.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Rab12 RAB12, member RAS oncogene family [ Mus musculus (house mouse) ]
• Official Symbol: Rab12
• Synonyms: Rab12; RAB12, member RAS oncogene family; C77700; AW555448; 2900054P15Rik; ras-related protein Rab-12; rab-13
• Gene ID: 19328
• mRNA Refseq: NM_024448
• Protein Refseq: NP_077768
• UniProt ID: P35283