Recombinant Mouse Pxylp1 Protein, Myc/DDK-tagged

• Cat.No.: Pxylp1-5269M
• Product Overview: Purified recombinant protein of mouse full-length 2-phosphoxylose phosphatase 1 (Pxylp1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Responsible for the 2-O-dephosphorylation of xylose in the glycosaminoglycan-protein linkage region of proteoglycans thereby regulating the amount of mature glycosaminoglycan (GAG) chains. Sulfated glycosaminoglycans (GAGs), including heparan sulfate and chondroitin sulfate, are synthesized on the so-called common GAG-protein linkage region (GlcUAbeta1-3Galbeta1-3Galbeta1-4Xylbeta1-O-Ser) of core proteins, which is formed by the stepwise addition of monosaccharide residues by the respective specific glycosyltransferases. Xylose 2-O-dephosphorylation during completion of linkage region formation is a prerequisite for the initiation and efficient elongation of the repeating disaccharide region of GAG chains.
• Molecular Mass: 54.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Pxylp1 2-phosphoxylose phosphatase 1 [ Mus musculus (house mouse) ]
• Official Symbol: Pxylp1
• Synonyms: Pxylp1; 2-phosphoxylose phosphatase 1; Ac; Acpl2; BB177120; 9430094M07Rik; C130099A20Rik; 2-phosphoxylose phosphatase 1; acid phosphatase-like 2; acid phosphatase-like protein 2; EC 3.1.3.2
• Gene ID: 235534
• mRNA Refseq: NM_153420
• Protein Refseq: NP_700469
• UniProt ID: Q8BHA9