Recombinant Mouse Prkx Protein, Myc/DDK-tagged

• Cat.No.: Prkx-5129M
• Product Overview: Purified recombinant protein of mouse full-length protein kinase, X-linked (Prkx), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Serine/threonine protein kinase regulated by and mediating cAMP signaling in cells. Acts through phosphorylation of downstream targets that may include CREB, SMAD6 and PKD1 and has multiple functions in cellular differentiation and epithelial morphogenesis. Regulates myeloid cell differentiation through SMAD6 phosphorylation. Involved in nephrogenesis by stimulating renal epithelial cell migration and tubulogenesis. Also involved in angiogenesis through stimulation of endothelial cell proliferation, migration and vascular-like structure formation.
• Molecular Mass: 40.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Prkx protein kinase, X-linked [ Mus musculus (house mouse) ]
• Official Symbol: Prkx
• Synonyms: PRKX; protein kinase, X-linked; cAMP-dependent protein kinase catalytic subunit PRKX; protein kinase X; protein kinase X-linked; PKA-related protein kinase; putative serine/threonine kinase; serine/threonine-protein kinase PRKX; PKX1; Pkare
• Gene ID: 19108
• mRNA Refseq: NM_016979
• Protein Refseq: NP_058675
• UniProt ID: Q922R0