Recombinant Mouse Ppp2ca Protein, Myc/DDK-tagged

Cat.No. : Ppp2ca-5077M
Product Overview : Purified recombinant protein of mouse full-length protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform (Ppp2ca), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
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Species : Mouse
Source : HEK293
Tag : DDK&Myc
Description : PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I. Activates RAF1 by dephosphorylating it at 'Ser-259'.
Molecular Mass : 36.1 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name Ppp2ca protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform [ Mus musculus (house mouse) ]
Official Symbol Ppp2ca
Synonyms PPP2CA; protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform; serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A-alpha; protein phosphatase 2a, catalytic subunit, alpha isoform; PP2A; R75353
Gene ID 19052
mRNA Refseq NM_019411
Protein Refseq NP_062284
UniProt ID P63330

Not For Human Consumption!

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