Recombinant Mouse Ppp2ca Protein, Myc/DDK-tagged

• Cat.No.: Ppp2ca-5077M
• Product Overview: Purified recombinant protein of mouse full-length protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform (Ppp2ca), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I. Activates RAF1 by dephosphorylating it at 'Ser-259'.
• Molecular Mass: 36.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Ppp2ca protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform [ Mus musculus (house mouse) ]
• Official Symbol: Ppp2ca
• Synonyms: PPP2CA; protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform; serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A-alpha; protein phosphatase 2a, catalytic subunit, alpha isoform; PP2A; R75353
• Gene ID: 19052
• mRNA Refseq: NM_019411
• Protein Refseq: NP_062284
• UniProt ID: P63330