Recombinant Mouse Pole3 Protein, Myc/DDK-tagged

• Cat.No.: Pole3-4987M
• Product Overview: Purified recombinant protein of mouse full-length polymerase (DNA directed), epsilon 3 (p17 subunit) (Pole3), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Accessory component of the DNA polymerase epsilon complex. Participates in DNA repair and in chromosomal DNA replication. Forms a complex with CHRAC1 and binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome-remodeling activity of ISWI/SNF2H and ACF1.
• Molecular Mass: 16.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Pole3 polymerase (DNA directed), epsilon 3 (p17 subunit) [ Mus musculus (house mouse) ]
• Official Symbol: Pole3
• Synonyms: POLE3; polymerase (DNA directed), epsilon 3 (p17 subunit); DNA polymerase epsilon subunit 3; YB-like protein 1; NF-YB-like protein; DNA polymerase II subunit 3; DNA polymerase epsilon, subunit 3; DNA polymerase epsilon subunit p17; YBL1; 1810034K18Rik
• Gene ID: 59001
• mRNA Refseq: NM_021498
• Protein Refseq: NP_067473
• UniProt ID: Q9JKP7