Recombinant Mouse Poldip3 Protein, Myc/DDK-tagged

• Cat.No.: Poldip3-4986M
• Product Overview: Purified recombinant protein of mouse full-length polymerase (DNA-directed), delta interacting protein 3 (Poldip3), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Is involved in regulation of translation. Is preferentially associated with CBC-bound spliced mRNA-protein complexes during the pioneer round of mRNA translation. Contributes to enhanced translational efficiency of spliced over nonspliced mRNAs. Recruits activated ribosomal protein S6 kinase beta-1 I/RPS6KB1 to newly synthesized mRNA. Involved in nuclear mRNA export; probably mediated by association with the TREX complex.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 46.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Poldip3 polymerase (DNA-directed), delta interacting protein 3 [ Mus musculus (house mouse) ]
• Official Symbol: Poldip3
• Synonyms: POLDIP3; polymerase (DNA-directed), delta interacting protein 3; polymerase delta-interacting protein 3; S6K1 Aly/REF-like target; polymerase delta interacting protein 46; SKAR; C77954; PDIP46; AA408269; AL022852; mKIAA1649; 1110008P04Rik; KIAA1649
• Gene ID: 73826
• mRNA Refseq: NM_178627
• Protein Refseq: NP_848742
• UniProt ID: Q8BG81