Recombinant Mouse PNPLA2 Protein, His (Fc)-Avi-tagged

• Cat.No.: PNPLA2-6888M
• Product Overview: Recombinant Mouse PNPLA2 with His (Fc)-Avi tag was expressed and purified

Specification

• Source: HEK293
• Species: Mouse
• Tag: His&Fc&Avi
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: ≥85% by SDS-PAGE
• Stability: Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: Pnpla2 patatin-like phospholipase domain containing 2 [ Mus musculus ]
• Official Symbol: PNPLA2
• Gene ID: 66853
• mRNA Refseq: NM_001163689.1
• Protein Refseq: NP_001157161.1
• UniProt ID: Q8BJ56

Reviews

05/14/2020

Quick and precise protein expression, a valuable asset.

09/09/2019

Exceptional protein purification, highly recommended for our research.

03/01/2018

Dependable mass spectrometry analysis, enhances our proteomics research.

Q&As

How does PNPLA2 influence energy homeostasis and fatty acid oxidation in muscle tissues?

PNPLA2 influences energy homeostasis in muscles, facilitating fatty acid oxidation for energy production.

How do alterations in PNPLA2 expression or activity affect cardiovascular health and the risk of atherosclerosis?

Changes in PNPLA2 activity affect cardiovascular health, potentially influencing the development of atherosclerosis.

How does PNPLA2 contribute to the regulation of hepatic lipid metabolism and the development of fatty liver disease?

PNPLA2 regulates liver lipid metabolism, impacting the development of fatty liver disease.

What is the impact of PNPLA2 mutations on the pathogenesis of lipid storage diseases?

Mutations in PNPLA2 can lead to lipid storage diseases by disrupting normal lipid metabolism.

What role does PNPLA2 play in the development and progression of obesity and related metabolic disorders?

PNPLA2 plays a significant role in obesity and metabolic syndrome, affecting lipid storage and energy balance.

What are the mechanisms by which PNPLA2 modulates inflammation and insulin sensitivity?

PNPLA2 modulates inflammation and insulin sensitivity, influencing metabolic health and the risk of diabetes.

How does PNPLA2 regulate lipid metabolism and triglyceride hydrolysis in adipose tissue?

PNPLA2 is crucial for lipid metabolism, breaking down triglycerides in adipose tissue for energy use.