Recombinant Mouse Platelet Factor 4
Cat.No. : | Pf4-152M |
Product Overview : | Recombinant Mouse CXCL4 produced inE.Coliis a single, non-glycosylated polypeptide chain containing 73 amino acids and having a molecular mass of 8.2 kDa. |
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Species : | Mouse |
Source : | E.coli |
Tag : | Non |
Description : | Platelet factor-4 is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair. Oncostatin-A is a member of the CXC chemocinfamily. Human PF4 is used for the proof of heparin-induced thrombocytopenia. Furthermore it is used as an inhibitor in the angiogenesis during tumor therapy. |
Amino Acid Sequence : | MGPEESD GDLSCVCVKT ISSGIHLKHI TSLEVIKAGR HCAVPQLIAT LKNGRKICLD RQAPLYKKVI KKILES. |
Physical Appearance : | Sterile Filtered white lyophilized powder. |
Formulation : | The Mouse CXCL4 protein was lyophilized from 1x PBS pH-7.4. |
Stability : | Mouse CXCL4 although stable at 25°C 1 week, should be stored desiccated below -18°C. Please prevent freeze-thaw cycles. |
Gene Name | Pf4 platelet factor 4 [ Mus musculus ] |
Synonyms | Pf4; platelet factor 4; Cxcl4; Scyb4; PF-4; C-X-C motif chemokine 4; chemokine (C-X-C motif) ligand 4 |
Gene ID | 56744 |
mRNA Refseq | NM_019932 |
Protein Refseq | NP_064316 |
UniProt ID | Q9Z126 |
Chromosome Location | 5 E1 |
Pathway | Chemokine signaling pathway; Cytokine-cytokine receptor interaction |
Function | chemokine activity; cytokine activity; heparin binding |
◆ Recombinant Proteins | ||
PF4-04H | Recombinant Human PF4 Protein | +Inquiry |
PF4-4388R | Recombinant Rat PF4 Protein | +Inquiry |
PF4-52H | Human Platelet Factor 4 | +Inquiry |
PF4-647P | Recombinant Pig PF4 protein, mFc-tagged | +Inquiry |
PF4-151H | Recombinant Human PF4 Protein, DYKDDDDK-tagged | +Inquiry |
◆ Native Proteins | ||
PF4-253H | Native Human Platelet Factor 4 | +Inquiry |
◆ Cell & Tissue Lysates | ||
PF4-3283HCL | Recombinant Human PF4 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
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