Recombinant Mouse Plat Protein, Myc/DDK-tagged

• Cat.No.: Plat-4907M
• Product Overview: Purified recombinant protein of mouse full-length plasminogen activator, tissue (Plat), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a key enzyme of the fibrinolytic pathway. The encoded protein undergoes proteolytic processing by plasmin to generate a heterodimeric serine protease that cleaves the proenzyme plasminogen to produce plasmin, a protease that is required to break down fibrin clots. Additionally, the encoded protein is involved in other biological processes such as synaptic plasticity, cell migration and tissue remodeling. Mice lacking the encoded protein display a reduction in long-term potentiation in hippocampus and conversely, transgenic mice overexpressing the encoded protein have increased and prolonged long-term potentiation.
• Molecular Mass: 63.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Plat plasminogen activator, tissue [ Mus musculus (house mouse) ]
• Official Symbol: Plat
• Synonyms: PLAT; plasminogen activator, tissue; tissue-type plasminogen activator; t-plasminogen activator; tPA; AU020998; AW212668; D8Ertd2e; MGC18508
• Gene ID: 18791
• mRNA Refseq: NM_008872
• Protein Refseq: NP_032898
• UniProt ID: P11214