Recombinant Mouse Pgam5 Protein, Myc/DDK-tagged

• Cat.No.: Pgam5-4817M
• Product Overview: Purified recombinant protein of mouse full-length phosphoglycerate mutase family member 5 (Pgam5), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Displays phosphatase activity for serine/threonine residues, and, dephosphorylates and activates MAP3K5 kinase. Has apparently no phosphoglycerate mutase activity. May be regulator of mitochondrial dynamics. Substrate for a KEAP1-dependent ubiquitin ligase complex. Contributes to the repression of NFE2L2-dependent gene expression. Acts as a central mediator for programmed necrosis induced by TNF, by reactive oxygen species and by calcium ionophore.
• Molecular Mass: 32.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Pgam5 phosphoglycerate mutase family member 5 [ Mus musculus (house mouse) ]
• Official Symbol: Pgam5
• Synonyms: Pgam5; phosphoglycerate mutase family member 5; 2610528A17Rik; serine/threonine-protein phosphatase PGAM5, mitochondrial; EC 3.1.3.16
• Gene ID: 72542
• mRNA Refseq: NM_001163538
• Protein Refseq: NP_001157010
• UniProt ID: Q8BX10