Recombinant Mouse Peli3 Protein, Myc/DDK-tagged

• Cat.No.: Peli3-4791M
• Product Overview: Purified recombinant protein of mouse full-length pellino 3 (Peli3), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates 'Lys-63'-linked polyubiquitination of IRAK1. Can activate AP1/JUN and ELK1. Not required for NF-kappa-B activation.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 48.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Peli3 pellino 3 [ Mus musculus (house mouse) ]
• Official Symbol: Peli3
• Synonyms: PELI3; pellino 3; E3 ubiquitin-protein ligase pellino homolog 3; pellino-3; protein pellino homolog 3; BC028931; A930011L17; 6030441F14Rik; MGC30417
• Gene ID: 240518
• mRNA Refseq: NM_172835
• Protein Refseq: NP_766423
• UniProt ID: Q8BXR6